QSAR Studies on Ant Malarial Activity of Diverse Set of Compounds for D6 Strain of P. falciparum

Autor:	D. Thakur, Vandana Khatod, C. D. Asthana, S. Thakur
Rok vydání:	2014
Předmět:	Quantitative structure–activity relationship Mefloquine Strain (biology) General Medicine Disease Biology Pharmacology medicine.disease Virology ANT parasitic diseases medicine Malaria medicine.drug
Zdroj:	SAMRIDDHI : A Journal of Physical Sciences, Engineering and Technology. 6:89-98
ISSN:	2454-5767 2229-7111
DOI:	10.18090/samriddhi.v6i2.1558
Popis:	Malaria spread by sporozoa of p.falciperum and is well known as an infectious lethal disease.Sometimes it causes death if the medicine is not given in time.Only a limited number of drugs can now prevent and cure malaria.For in vitro testing the clones D6 and NF54 of p. felciperum are most often used.These are resistant to present drugs like mefloquine.The data set based on the D6 strains consisting of 57 organic compounds was collected from different sources and their antimalarial activity is predicted by taking different parametric models.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::bae98967991310eb888dc6e0409b66a6 https://doi.org/10.18090/samriddhi.v6i2.1558 Zobrazit plný text záznamu