| Autor: |
F. Gyorkey, J. G. Sinkovics, J. E. Szakacs |
| Rok vydání: |
1993 |
| Předmět: |
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| Zdroj: |
Advances in Experimental Medicine and Biology ISBN: 9781461362975 |
| DOI: |
10.1007/978-1-4615-2980-4_35 |
| Popis: |
In this brief review a list of potential pathogens is provided that are associated with Kaposi’s sarcoma (KS) and may contribute to the initiation and/or maintenance of growth of KS cells. For the end result, which is the characteristic appearance and grouping of KS cells, the same growth factors are needed in a set sequence and combination. However, the pathogens inducing these growth factors may be different. Induction of the same growth factors by diverse pathogens can result in the generation of endothelial cell growth and transformation in sequence recognized as various subtypes of KS. Indeed there has to be an initiator of growth factor release from CD4 lymphocytes other than HIV in classical (Mediterranean) KS. On the other hand, HIV infection alone is not enough to induce KS: patients with hemophilia acquiring HIV infection through blood products die with AIDS but without developing KS. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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