A general and stereoselective approach to 14-membered cyclic bis-semicarbazones involving BF3-catalyzed amidoalkylation of 2-(trimethylsilyloxy)propene

Autor:	Anatoly Shutalev, Anastasia Fesenko
Rok vydání:	2022
Předmět:	Organic Chemistry Physical and Theoretical Chemistry Biochemistry
Zdroj:	Organic & Biomolecular Chemistry. 20:4569-4588
ISSN:	1477-0539 1477-0520
DOI:	10.1039/d2ob00644h
Popis:	An effective approach to 14-membered hexaaza macrocycles based on BF3-catalyzed amidoalkylation of 2-(trimethylsilyloxy)propene followed by reaction of the obtained 4-(3-oxobutyl)semicarbazones with N2H4 and TsOH-promoted cyclization is reported.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::baca70c5b6af05d1566e935f021686ce https://doi.org/10.1039/d2ob00644h Zobrazit plný text záznamu