Interactions Between the Renin-Angiotensin and the Kallikrein-Kinin System

Autor: G. Wiemer, P. Wohlfart
Rok vydání: 2004
Předmět:
Zdroj: Angiotensin Vol. II ISBN: 9783540406419
Popis: Angiotensin-I-converting enzyme (ACE) has turned out to be a central target molecule in the successful treatment of many important cardiovascular diseases. The value of ACE inhibitors as therapeutic options has grown with every year over the past 2 decades, but our knowledge regarding the underlying mechanisms also increased. Today it seems that multiple interactions into the renin-angiotensin (RAS) and the kallikrein-kinin (KKS) system exist. This chapter summarizes what is currently known about the se interactions between RAS and KKS, with a specific focus on two target organs: the endothelium and the heart
Databáze: OpenAIRE