Crystal solvates and polymorphs of N-(3-methylthio-1,2,4-thiadiazol-5-yl-aminocarbonylmethyl)cytisine

Autor:	K. K. Turgunov, B. Tashkhodjave, Kh. M. Shakhidoyatov, A. G. Tojiboev, T. F. Ibragimov, U. S. Makhmudov, V. A. Saprykina
Rok vydání:	2008
Předmět:	Chloroform Thermal decomposition General Chemistry Crystal structure Condensed Matter Physics Crystal Cytisine chemistry.chemical_compound Crystallography chemistry Molecule Hydrate Single crystal Food Science
Zdroj:	Journal of Inclusion Phenomena and Macrocyclic Chemistry. 61:71-76
ISSN:	1573-1111 0923-0750
Popis:	A polymorphs, crystallohydrate and crystallosolvates of N-(3-methylthio-1,2,4-thiadiazol-5-yl-aminocarbonylmethyl)cytisine, C16H19N5O2S2, with chloroform, methanol, benzene have been obtained and crystal structures have been determined by the method of single crystal X-ray diffraction. In the investigated crystals N-(3-methylthio-1,2,4-thiadiazol-5-yl-aminocarbonylmethyl)cytisine have taken four types of conformation due to intra-molecular rotations around N–C and C–C bonds. So free rotations in the molecule assisted in formation a different crystallosolvates and polymorphs depending on nature of solvents. The thermal decomposition of the hydrate and methanol solvated crystals was studied by means of a TG-DSC.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::baa35a918c8e352453502422405470bd https://doi.org/10.1007/s10847-007-9394-0 Zobrazit plný text záznamu Full text from SpringerLink