Autor: |
A. B. Mazloev, S. V. Klochkova, D. K. Obukhov, D. B. Nikityuk, T. A. Tsekhmistrenko |
Rok vydání: |
2019 |
Předmět: |
|
Zdroj: |
Journal of Anatomy and Histopathology. 7:88-93 |
ISSN: |
2225-7357 |
DOI: |
10.18499/2225-7357-2018-7-4-88-93 |
Popis: |
Objective– the study of age-related changes in the thickness of the cortex and its layers in the posterior lobe of the cerebellum of children.Material and methods.The work is performed on postmortem material (62 cerebellum), obtained from children aged from birth to 12 years who died as a result of injuries without brain damage. Using computer morphometry on the painted method Nissle frontal histological sections of cortex, taken in region right and left posterior quadrangular lobules (H VI) on top of the folia of cerebellum, was measured the cortical thickness and the thickness of molecular and granular layers. Analysis of quantitative data was performed at annual intervals.Results. The posterior lobe of the cerebellum the increase in the thickness of the cortex in the left hemisphere occurs in two stages: from birth to 1 year and then to 2 years, in the right hemisphere in three stages: from birth to 1 year, and 2 and 7 years. Right-sided asymmetry of the thickness of the cerebellar cortex observed in infants and children 7 years of age, thickness of granular layer in infants and children 9 years. Left-hand asymmetry is specific to cortical thickness and its molecular layer in children 12 months.Conclusion. The thickness of the cerebellar cortex and its layers in the area of the lobule H VI increases during early childhood, and in the right hemisphere also during the first childhood. Reducing the diameter of the cortex and layer in the posterior lobe of the cerebellum of children from birth to 12 years of age are not detected. |
Databáze: |
OpenAIRE |
Externí odkaz: |
|