Synthesis of sequential polypeptides containing lysine and tyrosine
| Autor: | S. St. Pierre, Murray Goodman, R. T. Ingwall |
|---|---|
| Rok vydání: | 1978 |
| Předmět: |
Organic Chemistry
Lysine Condensation Biophysics Solution polymerization macromolecular substances General Medicine environment and public health Biochemistry eye diseases Biomaterials enzymes and coenzymes (carbohydrates) chemistry.chemical_compound Monomer chemistry Organic chemistry Tyrosine hormones hormone substitutes and hormone antagonists Carbonic Anhydride |
| Zdroj: | Biopolymers. 17:1827-1835 |
| ISSN: | 1097-0282 0006-3525 |
| DOI: | 10.1002/bip.1978.360170802 |
| Popis: | Sequential polypeptides with the repeating units L-tyrosyl-L-lysyl, L-tyrosyl-(L-lysyl)2, and L-tyrosyl-(L-lysyl)3 have been synthesized by solution polymerization of the N-hydroxy-succinimide esters of the corresponding di-, tri-, and tetrapeptides. The monomers for the polytripeptide and polytetrapeptide were prepared by fragment condensation, using the mixed carbonic anhydride coupoling method. Moderately high molecular weight polypeptides were obtained. |
| Databáze: | OpenAIRE |
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