Electrochemical modeling of antioxidants action and determination of their activity

Autor:	O. S. Kruglyak, G. S. Shapoval
Rok vydání:	2011
Předmět:	Antioxidant medicine.medical_treatment Radical General Chemistry Electrochemistry Ascorbic acid Branching (polymer chemistry) Ferrous chemistry.chemical_compound chemistry medicine Organic chemistry Biologically active substances Hydrogen peroxide
Zdroj:	Russian Journal of General Chemistry. 81:1442-1448
ISSN:	1608-3350 1070-3632
Popis:	The method of pulse voltammetry was applied to the investigation of the antioxidant activity of sulfur-containing biologically active substances. Three models were considered to characterize the substances in aqueous medium: First, the interaction of antioxidants with a ferrous ion to characterize the preventive activity on the initiation stage of free radical oxidation, second and third describing the interaction of an antioxidant with electrochemically generated hydroxy radicals and hydrogen peroxide, to characterize the inhibitory activity in the initial stages of propagation and branching of the chain of free radical oxidation. A synergistic effect of ascorbic acid and other studied compounds at their combined action on hydroxy radicals and hydrogen peroxide was revealed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::ba42514878888c90a4308d5dbb4ae387 https://doi.org/10.1134/s1070363211070073 Zobrazit plný text záznamu Plný text ve formátu PDF