Electrochemical modeling of antioxidants action and determination of their activity
Autor: | O. S. Kruglyak, G. S. Shapoval |
---|---|
Rok vydání: | 2011 |
Předmět: | |
Zdroj: | Russian Journal of General Chemistry. 81:1442-1448 |
ISSN: | 1608-3350 1070-3632 |
Popis: | The method of pulse voltammetry was applied to the investigation of the antioxidant activity of sulfur-containing biologically active substances. Three models were considered to characterize the substances in aqueous medium: First, the interaction of antioxidants with a ferrous ion to characterize the preventive activity on the initiation stage of free radical oxidation, second and third describing the interaction of an antioxidant with electrochemically generated hydroxy radicals and hydrogen peroxide, to characterize the inhibitory activity in the initial stages of propagation and branching of the chain of free radical oxidation. A synergistic effect of ascorbic acid and other studied compounds at their combined action on hydroxy radicals and hydrogen peroxide was revealed. |
Databáze: | OpenAIRE |
Externí odkaz: |