Causes of death after therapy for early stage Hodgkin's disease entered on EORTC protocols

Autor: M. Hayat, J.H. Meerwaldt, Jean-Marc Cosset, B. de Pauw, M J Burgers, José Thomas, R. Regnier, J. Lutsman-Marechal, D. Bron, E.M. Noordijk, A. Tanguy, E. van der Schueren, R. Somers, M. Tubiana, Michel Henry-Amar, M. Monconduit, Patrice Carde
Rok vydání: 1990
Předmět:
Zdroj: International Journal of Radiation Oncology*Biology*Physics. 19:1155-1157
ISSN: 0360-3016
Popis: The risk of dying from different causes after Hodgkin's disease (HD) therapy has been quantified from a series of 1,449 patients with early stages included in four successive clinical trials conducted by the European Organization for Research and Treatment of Cancer (EORTC) Lymphoma Cooperative Group since 1963. Overall, 240 patients died and the 15-year survival rate was 69% whereas the expected rate was 95%. The standardized mortality ratio (SMR) technique was used to quantify excess deaths as a function of time since first therapy. At each interval, SMR was significantly increased, giving: 0–3 year, 8.86 ( p p p p p p
Databáze: OpenAIRE