Cytotoxic derivatives of (22R,23R)-dihydroxystigmastane

Autor:	Galina E. Morozevich, Vladimir P. Timofeev, Misharin AIu, F. V. Drozdov, Mekhtiev Ar
Rok vydání:	2007
Předmět:	Hep G2 medicine.anatomical_structure Chemistry Organic Chemistry Mammary gland Immunology medicine Carcinoma Cytotoxic T cell Cytotoxicity medicine.disease Biochemistry Molecular biology
Zdroj:	Russian Journal of Bioorganic Chemistry. 33:326-333
ISSN:	1573-9163 1068-1620
Popis:	(22R,23R)-22,23-dihydroxystigmast-4-en-3-one, (22R,23R)-22,23-dihydroxystigmast-4-en-3,6-dione, (22R,23R)-3β,5α,6β,22,23-pentahydroxystigmastane, (22R,23R)-5α,6α-oxido-3β,22,23-trihydroxystigmastane, (22R,23R)-5β,6β-oxido-3β,22,23-trihydroxystigmastane, and (22R,23R)-3β,6β,22,23-tetrahydroxystigmast-4-ene were synthesized. Their cytotoxicities were comparatively studied using the MCF-7 line of carcinoma cells of human mammary gland and cells of human hepatoma of the Hep G2 line.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::b9f935e1266e7a2ba8a50b2c963eee93 https://doi.org/10.1134/s1068162007030090 Zobrazit plný text záznamu Full text from SpringerLink