Clinical and laboratory outcome after surgical treatment of single congenital extrahepatic portosystemic shunt using ameroid constrictor in 25 dogs
| Autor: | Ladislav Stehlík, Pavel Proks, Andrea Nečasová, Alois Nečas, Jana Lorenzová, Zita Filipejová |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
General Veterinary Bile acid 040301 veterinary sciences business.industry medicine.drug_class 0402 animal and dairy science 04 agricultural and veterinary sciences 040201 dairy & animal science Surgery 0403 veterinary science Medicine Portosystemic shunt business Surgical treatment |
| Zdroj: | Acta Veterinaria Brno. 89:357-365 |
| ISSN: | 1801-7576 0001-7213 |
| Popis: | The objective of the study was to evaluate the clinical and laboratory outcome after the surgical treatment of a single congenital extrahepatic portosystemic shunt using an ameroid constrictor. Patient medical records were reviewed in retrospect. Data on the signalment, clinical signs, preoperative bile acid stimulation test and ammonia concentration were recorded. The surgical treatment success rate was evaluated by mortality in the perioperative and short-term postoperative period and by the long-term clinical outcome. Bile acid stimulation test and ammonia concentration were also analysed 2–3 days, 4–6 weeks, and 6–8 weeks postoperatively. No patient died in the selected periods. The long-term clinical outcome was excellent in 15 out of 20 patients, good in 3 out of 20 patients and poor in 2 out of 20 patients. Preprandial bile acid concentration was elevated in 96.00%, postprandial bile acid concentration in 100.00% and ammonia concentration in 80.95% of patients preoperatively. A significant decrease was found in postprandial bile acid and ammonia 2–3 days postoperatively and in preprandial bile acid 4–6 weeks postoperatively. A significant decrease in liver function parameters in days post operation indicates a rapid restoration of hepatic function. The surgical treatment of a single extrahepatic portosystemic shunt using an ameroid constrictor is a successful method of treatment for this type of portosystemic shunt, with as much as 75.00% of the patients having an excellent long-term clinical outcome. |
| Databáze: | OpenAIRE |
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