| Autor: |
Guang-zhi Zeng, Wen-lan Duan, Qiang Wang, Jia-hao Lou, Ji-hong Wang, Zi-yan Zhao, Jun-lin Yin |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
Tetrahedron Letters. 87:153543 |
| ISSN: |
0040-4039 |
| DOI: |
10.1016/j.tetlet.2021.153543 |
| Popis: |
A novel sesquiterpenoid, named Cyperensol A (1), was isolated from the rhizomes of Cyperus rotundus L. Its structure was elucidated extensively by the spectroscopic analysis. Possible biosynthetic pathway of 1 was proposed. Compound 1 showed inhibitory activity on IL-6 induced activation of JAK/STAT3 signaling pathway with IC50 value of 189.37 ± 7.20 μM. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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