Lecanicillolide, an α-pyrone substituted spiciferone from the fungus Lecanicillium sp. PR-M-3

Autor:	Zaiying Wang, Zhan-Lin Li, Huaqi Pan, Shengshuang Chen, Hui-Ming Hua, Aihong Han, Jiao Bai, Xia-Nan Sang
Rok vydání:	2017
Předmět:	biology 010405 organic chemistry Chemistry Stereochemistry Organic Chemistry Lecanicillium sp Fungus 010402 general chemistry biology.organism_classification 01 natural sciences Biochemistry Pyrone 0104 chemical sciences chemistry.chemical_compound Drug Discovery Spectral data
Zdroj:	Tetrahedron Letters. 58:740-743
ISSN:	0040-4039
DOI:	10.1016/j.tetlet.2017.01.023
Popis:	A novel α-pyrone substituted spiciferone, lecanicillolide (1), was isolated along with structurally related known compounds 2–4 from the fungus Lecanicillium sp. PR-M-3. The structure of lecanicillolide was elucidated by UV, IR, HRESIMS, and NMR spectral data, ECD analysis and confirmed by single-crystal X-ray diffraction. A plausible biosynthetic pathway for lecanicillolide was also proposed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::b9d44d79bbcde3cb0b54a8b8d70f58d0 https://doi.org/10.1016/j.tetlet.2017.01.023 Zobrazit plný text záznamu Full Text from ScienceDirect