ChemInform Abstract: Mechanosynthesis of Amides in the Total Absence of Organic Solvent from Reaction to Product Recovery

Autor:	Jean Martinez, Thomas Reidon, Thomas-Xavier Métro, Frédéric Lamaty, Julien Bonnamour, Jordi Sarpoulet
Rok vydání:	2013
Předmět:	Active ingredient chemistry.chemical_compound chemistry Organic solvent Teriflunomide Product recovery Organic chemistry General Medicine Mechanosynthesis
Zdroj:	ChemInform. 44
ISSN:	0931-7597
DOI:	10.1002/chin.201313031
Popis:	A fast and efficient mechanochemical approach for the synthesis of carboxylic amides in the total absence of any organic solvent is realized and successfully applied to the preparation of the active pharmaceutical ingredient teriflunomide (IX).
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::b9d004aca419908ddf354eae3c0186bc https://doi.org/10.1002/chin.201313031 Zobrazit plný text záznamu Plný text