Lipid‐based nutrient supplements for pregnant women reduce newborn stunting in Bangladesh (256.6)

Autor: Janet M Peerson, Susana L Matias, Sohrab Hussain, K G Dewey, Camila M Chaparro, Joseph T. Cummins, Stephen Vosti, Louise T Day, Rina Rani Paul, Stacy L. Saha, Malay K Mridha, Kassandra L. Harding
Rok vydání: 2014
Předmět:
Zdroj: The FASEB Journal. 28
ISSN: 1530-6860
0892-6638
DOI: 10.1096/fasebj.28.1_supplement.256.6
Popis: Maternal undernutrition and newborn stunting (birth length-for-age z-score < -2) are common in Bangladesh. In the Rang-Din Nutrition Study, a cluster-randomized effectiveness trial underway in northwest Bangladesh, pregnant women received either a) iron & folic acid (IFA) or b) lipid-based nutrient supplement (LNS, 20 g/d, 118 kcal) designed to enrich local diets of pregnant women with essential fatty acids, high-quality protein and 22 micronutrients. Women (n=4011) were enrolled at 13.1 ± 3.4 wk gestation; 40% were nulliparous and 31% were underweight (BMI < 18.5 kg/m2). In the full sample, there were significant reductions in newborn stunting [18.6 vs. 22.5%, adjusted relative risk (ARR)=0.83 (0.70, 0.96)] and small head circumference (HC z-score < -2) [20.8 vs. 24.7%, ARR=0.82 (0.71, 0.95)] in the LNS vs. IFA group; the difference in low birth weight was marginally significant (36.8 vs. 39.1%, p=0.087). LNS distribution was interrupted for 10 wk in 2012; among women who gave birth before the interrupti...
Databáze: OpenAIRE