| Popis: |
The increasing use of limb-sparing surgery for major tumor excisions has created a demand for a reliable method of bridging large bony gaps. Conventional grafts require long periods of immobilization and often fail, especially when very large defects are bridged or the recipient bed is poorly vascularized. Microsurgery can be used to reestablish the blood supply to bone autografts, thus circumventing much of the repair process. Clinically, vascularized grafts heal faster, hypertrophy more, and are more reliable in poorly vascularized beds. Recent animal experiments have not duplicated the excellent results claimed in clinical studies, particularly with regard to hypertrophy. These experimental models use non-weightbearing grafts or grafts shielded by plates. The ability to hypertrophy rapidly is a key advantage for a bone graft since it reduces the immobilization period and lessens complications. |
