Prophylactic antibioitic use during dialysis catheter exchange
Autor: | E. Lacson, Franklin W. Maddux, Lin Ma, L.R. Petrusky, E. Barzel, G.S. Pressman, G. Miller |
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Rok vydání: | 2013 |
Předmět: |
medicine.medical_specialty
business.industry Nausea medicine.drug_class medicine.medical_treatment Antibiotics Cefazolin Dialysis catheter Surgery Route of administration Anesthesia Ambulatory medicine Vomiting Radiology Nuclear Medicine and imaging medicine.symptom Cardiology and Cardiovascular Medicine business Dialysis medicine.drug |
Zdroj: | Journal of Vascular and Interventional Radiology. 24:S42 |
ISSN: | 1051-0443 |
DOI: | 10.1016/j.jvir.2013.01.093 |
Popis: | Purpose To determine if prophylactic antibiotic use lowers the incidence of infection in the first week following tunneled dialysis catheter exchange. Materials and Methods Our 28 ambulatory surgery centers performed dialysis catheter exchanges for poorly functiong catheters. Some physicians give prophylactic antibiotics and some do not. Initiated as part of our QA program, and an MOC project, we evaulated each patient's outcome one week after their procedure. Data recorded when the procedures were performed included presence of preexisting infection, use of antibiotic, antibiotic type, route of administration, and timing of administration. Follow-up phone calls scheduled 6-8 days after intervention, were made to each patient's dialysis center to determine the presence of the following complications: infection, bleeding, nausea/vomiting, respiratory difficulty, and pain. This information was enteried into a central database. The QA/MOC team assessed the data. A WIRB exemption was obtained for publication of a retrospective analysis of the database from 1/1/2010 through 12/31/2011. All patient identifiers were removed and the database was submitted for statistical analysis. Only patients without preexisting infection were included in the analysis. Results There was a significant decrease in the rate of infection in patients who received IV antibiotics, primarily cefazolin 1gm, given pre-procedure or intraprocedure just prior to the intervention. Oral antibiotics given peri-procedure did not decrease infection rates. There was no significant difference in other rates of complications between those who did and did not receive antibiotics. Conclusion Intravenous cefazolin given prophylactically just prior to tunneled dialysis catheter exchange significantly reduces the rate of infection at one week. Table 1 |
Databáze: | OpenAIRE |
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