Directed lithiation of N-(tert-butoxycarbonyl)aminoisoxazole: synthesis of 4-substituted aminoisoxazoles

Autor:	Toshiro Konoike, Yoshitaka Araki, Yasuhiko Kanda
Rok vydání:	1996
Předmět:	chemistry.chemical_compound Chemistry Organic Chemistry Drug Discovery Electrophile Isoxazole Biochemistry Combinatorial chemistry
Zdroj:	Tetrahedron Letters. 37:3339-3342
ISSN:	0040-4039
Popis:	Directed lithiation of 3-(Boc-amino)isoxazole 4 and 5-(Boc-amino)isoxazole 9 is described. Dilithioisoxazoles reacted with a variety of electrophiles to give the corresponding 4-substituted isoxazoles.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::b9b6689850a71402c030d364aaed0328 https://doi.org/10.1016/0040-4039(96)00476-5 Zobrazit plný text záznamu Full Text from ScienceDirect