Ion mobility mass spectrometry and molecular dynamics simulations unravel the conformational stability of zinc metallothionein-2 species

Autor:	Manuel David Peris-Díaz, Alexey Barkhanskiy, Ellen Liggett, Perdita Barran, Artur Krężel
Rok vydání:	2023
Předmět:	Materials Chemistry Metals and Alloys Ceramics and Composites General Chemistry Catalysis Surfaces Coatings and Films Electronic Optical and Magnetic Materials
Zdroj:	Chemical Communications. 59:4471-4474
ISSN:	1364-548X 1359-7345
DOI:	10.1039/d2cc06559b
Popis:	We present a molecular dynamics approach to explore the conformational landscape of proteins analyzed by ion mobility-mass spectrometry, providing new insights into the structural properties of metallothioneins, a cellular zinc buffer system.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::b9b3a20de1b9eaeda937d66b2cde66f1 https://doi.org/10.1039/d2cc06559b Zobrazit plný text záznamu