Response to Letter Regarding Article, 'Predictors of Response to Cardiac Resynchronization Therapy in The Multicenter Automatic Defibrillator Implantation Trial With Cardiac Resynchronization Therapy (MADIT-CRT)'

Autor: Elyse Foster, Wojciech Zareba, Timothy Shinn, Arthur J. Moss, David J. Wilber, Jeffrey J. Goldberger, Scott McNitt, Helmut U. Klein, Ilan Goldenberg, Alon Barsheshet, Jonathan S. Steinberg, W. Jackson Hall, Scott D. Solomon, Peter Santucci
Rok vydání: 2012
Předmět:
Zdroj: Circulation. 125
ISSN: 1524-4539
0009-7322
DOI: 10.1161/circulationaha.112.096966
Popis: We agree with Varma et al that the findings of our current Multicenter Automatic Defibrillator Implantation Trial With Cardiac Resynchronization Therapy (MADIT-CRT) substudy (regarding factors associated with response to cardiac resynchronization therapy with a defibrillator (CRT-D)1 and the previous MADIT-CRT report by Singh et al (regarding the effect of left ventricular [LV] lead position on clinical outcomes in the same trial)2 may appear contradictory. However, caution is necessary in comparing the results of the 2 studies for the following reasons. (1) In the present study, we identified 7 factors associated with significant reductions in left ventricular volumes (ie, echocardiographic response) in the study patients treated with CRT-D and used …
Databáze: OpenAIRE