A new practical method for regioselective nucleophilic aromatic alkylation of ortho- or para-methoxy-substituted aromatic esters with Grignard reagents

Autor:	Tomoyuki Kojima, Izumi Yamamoto, Tatsuomi Matsuoka, Hiyoshizo Kotsuki, Takeshi Ohishi
Rok vydání:	2001
Předmět:	chemistry.chemical_classification Ester derivatives Aryl Organic Chemistry Regioselectivity Alkylation Biochemistry Medicinal chemistry Toluene chemistry.chemical_compound chemistry Nucleophile Reagent Drug Discovery lipids (amino acids peptides and proteins) Alkyl
Zdroj:	Tetrahedron Letters. 42:1709-1712
ISSN:	0040-4039
DOI:	10.1016/s0040-4039(00)02330-3
Popis:	A new practical method for the regioselective nucleophilic aromatic alkylation of o - or p -methoxy-substituted aromatic carboxylic acids via their triethylcarbinyl ester derivatives by conducting the reactions with alkyl/aryl Grignard reagents in toluene has been developed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::b99c989906b7b860333f2c385d2d288d https://doi.org/10.1016/s0040-4039(00)02330-3 Zobrazit plný text záznamu Full Text from ScienceDirect