Adrenoleukodystrophy initially presenting with symptoms of dementia
| Autor: | Kenji Nobuhara, Tokio Ohara, Gaku Okugawa, Chiharu Tamagaki, Tetsuji Sakata, Katsunori Takase, Akira Murata, Toshihiko Kinoshita |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
medicine.medical_specialty
Pathology White matter alterations medicine.diagnostic_test business.industry Magnetic resonance imaging Single-photon emission computed tomography medicine.disease White matter Psychiatry and Mental health medicine.anatomical_structure Neuroimaging mental disorders medicine Dementia Adrenoleukodystrophy Disease process Radiology Geriatrics and Gerontology business Gerontology |
| Zdroj: | Psychogeriatrics. 7:163-165 |
| ISSN: | 1479-8301 1346-3500 |
| DOI: | 10.1111/j.1479-8301.2007.00195.x |
| Popis: | There is growing consensus that dementia caused by white matter alterations is called ‘white matter dementia’. Because the symptoms of adrenoleukodystrophy (ALD) are associated with diffuse white matter dysfunction, ALD is categorized as white matter dementia. Herein, we describe the case of a 47-year-old man affected by ALD whose symptoms first appeared a few years earlier in the form of deteriorating personality and memory disturbances, heralded by neurological symptoms. On neuroimaging, a discrepancy was found between magnetic resonance imaging and single photon emission computed tomography in the early stage of the disease process. We suggest that this discrepancy may be an important finding in the diagnosis of early stage white matter dementia. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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