AlCl3-Catalyzed Intramolecular Hydroarylation of Arenes with Alkynes
| Autor: | Hao Guo, Guangxin Gu, Yu Wang, Ruiwen Jin, Yang Li, Dawen Xu |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Reaction mechanism
010405 organic chemistry Chemistry Organic Chemistry Electrophilic aromatic substitution 010402 general chemistry 01 natural sciences Combinatorial chemistry 0104 chemical sciences Catalysis Metal visual_art Intramolecular force visual_art.visual_art_medium Organic chemistry Lewis acids and bases Phenanthrenes |
| Zdroj: | Synlett. 28:2159-2162 |
| ISSN: | 1437-2096 0936-5214 |
| DOI: | 10.1055/s-0036-1588479 |
| Popis: | Herein, we wish to report the main-group metal Lewis acid catalyzed intramolecular hydroarylation of arenes with alkynes. This cyclization proceeds efficiently in the presence of a catalytic amount of AlCl3, affording phenanthrenes in moderate to excellent yields. The catalyst is cheap and nontoxic. The functional-group tolerance is high. A plausible electrophilic aromatic substitution reaction mechanism is proposed for this transformation. |
| Databáze: | OpenAIRE |
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