Inhibition of the Herpes Simplex Virus Thymidine Kinase by 5 Substituted Thymidine Analogues. Comparison of the Types 1 and 2 Enzymes

Autor: Richard Cosstick, A. Stanley Jones, Colin Picton, Albert Jaxa Chamiec, Iain S. Sim, Richard T. Walker
Rok vydání: 1988
Předmět:
Zdroj: Nucleosides and Nucleotides. 7:129-135
ISSN: 0732-8311
Popis: A series of 5′-substituted-deoxypyrimidine nucleosides were examined for their ability to inhibit the thymidine kinases of types 1 and 2 herpes simplex virus; structure activity relationships were determined.
Databáze: OpenAIRE