Efficient synthesis of tetracyclic γ-lactams via gold-catalyzed oxidative cyclization of alkenyl diynes

Autor: Chong-Yang Shi, Ji-Jia Zhou, Pan Hong, Bo-Han Zhu, Feng-Lin Hong, Peng-Cheng Qian, Qing Sun, Xin Lu, Long-Wu Ye
Rok vydání: 2022
Předmět:
Zdroj: Organic Chemistry Frontiers. 9:2557-2562
ISSN: 2052-4129
DOI: 10.1039/d2qo00123c
Popis: An efficient gold-catalyzed cascade cyclization of alkenyl diynes involving alkyne oxidation, carbene-alkyne metathesis and cyclopropanation has been developed, affording various tetracyclic γ-lactams in moderate to good yields.
Databáze: OpenAIRE