Bis-deoxygenation of methyl 3,6-anhydro-D-pyranosides

Autor:	Christopher J. France, Ian M. McParlane, Christopher G. Newton, Philippe Pitchen, Derek H.R. Barton
Rok vydání:	1991
Předmět:	chemistry.chemical_classification chemistry.chemical_compound chemistry Product (mathematics) Galactose Organic Chemistry Drug Discovery Glycoside Reaction intermediate Biochemistry Medicinal chemistry Deoxygenation
Zdroj:	Tetrahedron. 47:6381-6388
ISSN:	0040-4020
DOI:	10.1016/s0040-4020(01)86566-2
Popis:	The synthesis and radical reduction of thiocarbonyl derivatives of methyl 3,6-anhydro pyranosides has been studied in the α-D-gluco, α-D-manno and β-D-galacto series. A cyclic intermediate is proposed to explain the fact that bis-deoxygenation only occurred in the galactose series, providing a 3 step synthesis of the desired product 1b .
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::b97cea85e70b0e1eef87a24cc204fce8 https://doi.org/10.1016/s0040-4020(01)86566-2 Zobrazit plný text záznamu