ANTIBACTERIAL ACTIVITY OF BIOACTIVE STREPTOMYCES SPECIES MPPO-02 AGAINST CLINICAL ISOLATES OF BURN, DENTAL CARIES AND URINARY TRACT INFECTIONS

Autor: Manasa M, Onkarappa R, Pallavi S, Prashith Kekuda T.R
Rok vydání: 2014
Předmět:
Zdroj: Journal of Biological & Scientific Opinion. 2:57-61
ISSN: 2321-6328
DOI: 10.7897/2321-6328.02113
Popis: The present study was conducted to determine antibacterial activity of ethyl acetate extract ob tained from the fermentation broth of bioactive Streptomyces species MPPO - 02 previously isolated from a rhizosphere soil of Mahishi, Karnataka, India. Agar well diffusion assay was performed to investigate inhibitory effect of ethyl acetate extract against a total of 15 clinical isolates from burn, dental caries and urinary tract infection. The extract was found inhibitory against all test bacteria but to a varied extent. Gram positive bacteria were found more susceptible to extract when compared to Gram ne gative bacteria. The isolate MPPO - 02 can be exploited for the development of agents active against pathogenic microorganisms. Further studies on purification of active principles from solvent extract, their characterization and inhibitory activity are to b e carried out.
Databáze: OpenAIRE