Reactions of β-Carbonylethylthiosulfhtes and β-Carbamoylethyl Disulfides with Amines

Autor:	Ranko Kiyofuji, Seigoro Hayashi, Mitsuru Furukawa, Takeshi Yuki, Yoko Kojima
Rok vydání:	1973
Předmět:	chemistry.chemical_compound Aqueous solution chemistry Sodium Drug Discovery Disulfide bond Anhydrous chemistry.chemical_element Organic chemistry General Chemistry General Medicine Cyclohexylamine
Zdroj:	Chemical and Pharmaceutical Bulletin. 21:811-816
ISSN:	1347-5223 0009-2363
DOI:	10.1248/cpb.21.811
Popis:	The reactions of sodium 2-phenylcarbamoylethylthiosulfate, sodium 2-cyclohexylcarbamoylethylthiosulfate and sodium 2-benzoylethylthiosulfate with aqueous alkylamines were attempted and found to give the corresponding N-β-carbonylethyl-N-alkylamines and sometimes bis (β-carbonylethyl) sulfides, though the same reactions in anhydrous state is known to give the corresponding disulfides as the only product isolated. The reaction between bis (2-phenylcarbamoylethyl) disulfide or bis (2-cyclohexylcarbamoylethyl) disulfide and aqueous cyclohexylamine was also attempted under similar conditions and found to give the corresponding sulfides. The mechanisms of these reactions were also discussed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::b965a27141b5e3dbcecac19e90264e84 https://doi.org/10.1248/cpb.21.811 Zobrazit plný text záznamu