Palladin Mutation Causes Familial Pancreatic Cancer and Suggests a New Cancer Mechanism

Autor: Dowen, Sally, Moyes, Kara White, Otey, Carol A, George, Ryan D, Bronner, Mary P, Crispin, David A, Crnogorac-Jurcevic, Tatjana, Whitcomb, David C, Chen, Ru, Brentnall, Teresa A, Pogue-Geile, Kay L
Jazyk: angličtina
Předmět:
Popis: Pancreatic cancer is a deadly disease. Discovery of the mutated genes that cause the inherited form(s) of the disease may shed light on the mechanism(s) of oncogenesis. Previously we isolated a susceptibility locus for familial pancreatic cancer to chromosome location 4q32–34. In this study, our goal was to discover the identity of the familial pancreatic cancer gene on 4q32 and determine the function of that gene.
Databáze: OpenAIRE