Morphological and functional characteristics of human pituitary lactotrophic adenomas in cell cultures

Autor: Elizarova Gp, E. I. Marova, Komolov Is, E. E. Makarovskaya, S. Yu. Kasumova, A. A. Bulatov, S. Yu. Serpukhovitin
Rok vydání: 1994
Předmět:
Zdroj: Bulletin of Experimental Biology and Medicine. 118:1241-1244
ISSN: 1573-8221
0007-4888
DOI: 10.1007/bf02444635
Popis: Some features of the morphological cellular structure of prolactin secreting human pituitary adenomas and their secretion of prolactin and somatotropic hormone in primary suspension cultures were investigated. A possiblein vitro proliferation of lactotrophs was established. The inhibitory effect of somatostatin and its synthetic analog sandostatin, on prolactin secretion in prolactinomas was found to be less than in somatotropic hormone-secreting pituitary tumors.
Databáze: OpenAIRE