Morphological and functional characteristics of human pituitary lactotrophic adenomas in cell cultures
Autor: | Elizarova Gp, E. I. Marova, Komolov Is, E. E. Makarovskaya, S. Yu. Kasumova, A. A. Bulatov, S. Yu. Serpukhovitin |
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Rok vydání: | 1994 |
Předmět: |
endocrine system
medicine.medical_specialty Somatotropic cell Pituitary tumors General Medicine Biology medicine.disease General Biochemistry Genetics and Molecular Biology In vitro Prolactin Prolactin cell Endocrinology Somatostatin Pituitary adenoma Internal medicine medicine Secretion hormones hormone substitutes and hormone antagonists |
Zdroj: | Bulletin of Experimental Biology and Medicine. 118:1241-1244 |
ISSN: | 1573-8221 0007-4888 |
DOI: | 10.1007/bf02444635 |
Popis: | Some features of the morphological cellular structure of prolactin secreting human pituitary adenomas and their secretion of prolactin and somatotropic hormone in primary suspension cultures were investigated. A possiblein vitro proliferation of lactotrophs was established. The inhibitory effect of somatostatin and its synthetic analog sandostatin, on prolactin secretion in prolactinomas was found to be less than in somatotropic hormone-secreting pituitary tumors. |
Databáze: | OpenAIRE |
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