ANTIMICROBIAL, ANTIOXIDANT AND CYTOTOXIC EVALUATION OF VARIOUS EXTRACTS OF IFLOGA SPICATA (FORSSK.) SCH.BIP

Autor:	A. K. Awan, S. Jan, Nawshad Muhammad, F. Ullah, Y. M. Khan, Syed A. A. Rizvi
Rok vydání:	2021
Předmět:	Chloroform Antioxidant DPPH Mechanical Engineering General Chemical Engineering medicine.medical_treatment Ethyl acetate General Chemistry Antimicrobial chemistry.chemical_compound chemistry Phytochemical medicine TBARS Food science Hydrogen peroxide
Zdroj:	Latin American Applied Research - An international journal. 51:277-283
ISSN:	1851-8796 0327-0793
Popis:	The current study reveals the pharmacological and phytochemical potential of different solvent fractions of Ifloga spicata. Antimicrobial and free radical scavenging activities, DPPH (1, 1-diphenyl-2-picrylhydrazyl), hydrogen peroxide scavenging assay, and cytotoxic effects of plant samples on lymphocytes stressed with hydrogen were performed. Ifloga spicata ethyl acetate fraction markedly showed higher antibacterial potential against P. aeruginosa (ATCC 27853) and E. Coli (ATCC 25922) bacteria. While higher antifungal potential was shown by the chloroform fraction against all three different a strain A. fumigates (ATCC 204305), A. flavus (ATCC 9643) and A. niger (ATCC 16404) as compared to others fractions of sample. DPPH maximum antioxidant potential was noted for methanolic extract followed by ethyl acetate and chloroform. Similarly, hydrogen peroxide effect was significantly decreased by ethyl acetate fraction. In blood lymphocytes the raise in ROS and TBARS level due to stress given by H2O2 was also recovered by different extracts of I. spicata. The decrease level of CAT, SOD and POD was also restored
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::b925dc55700dd667fbedb7b753e46ee7 https://doi.org/10.52292/j.laar.2021.733 Zobrazit plný text záznamu