Genicular nerve block in rheumatoid arthritis: a randomized clinical trial
| Autor: | Ahmed I. Maaty, Ahmed M. Elsaman, Ahmed Hamed |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
musculoskeletal diseases
Knee arthritis medicine.medical_specialty Triamcinolone acetonide Visual analogue scale business.industry medicine.medical_treatment General Medicine medicine.disease Rheumatology law.invention Tenderness Randomized controlled trial law Internal medicine Rheumatoid arthritis medicine Nerve block medicine.symptom business medicine.drug |
| Zdroj: | Clinical Rheumatology. 40:4501-4509 |
| ISSN: | 1434-9949 0770-3198 |
| Popis: | This study highlights the effect of a genicular nerve block (GNB) on pain, function, and inflammation outcome measures in rheumatoid arthritis (RA) knees. A total of sixty-four patients diagnosed with RA using ACR/EULAR 2010 criteria with unilateral persistent knee arthritis were recruited to the study. They were randomly assigned into two groups: group 1 received GNB and group 2 received intra-articular triamcinolone. Both groups were examined by the SOLAR scoring system, visual analog scale (VAS), and Lysholm score at 0, 2, and 12 weeks. A semi-quantitative score was used to assess the tenderness and swelling at the same intervals. Function and inflammation improved significantly in group 2 at a 2-week interval as compared to group 1, whereas pain improved in both groups with non-significant differences. After 12 weeks, group 1 showed significant improvement as compared with group 2 for the three outcome measures. Neither the disease activity nor the current medication was related to the GNB effect. Disease duration was negatively related to GNB-induced improvement. GNB is a new promising local therapy for RA to control pain, improve function, and alleviate inflammation of the knee joint. Although it has a relatively short-term effect, yet it has outperformed the steroid effect. |
| Databáze: | OpenAIRE |
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