Chronological lifespan regulation of Saccharomyces cerevisiae by leucine biosynthesis pathway genes via TOR1 and COX2 expression regulation

Autor:	Choco Michael Gorospe, Sung-Lim Yu, Mi-Sun Kang, Sung-Keun Lee
Rok vydání:	2018
Předmět:	0301 basic medicine Health Toxicology and Mutagenesis media_common.quotation_subject Saccharomyces cerevisiae Protein metabolism Toxicology Pathology and Forensic Medicine 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine General Pharmacology Toxicology and Pharmaceutics Gene media_common Leucine biosynthesis biology Public Health Environmental and Occupational Health Longevity biology.organism_classification Yeast Cell biology Insulin receptor 030104 developmental biology chemistry 030220 oncology & carcinogenesis biology.protein Leucine
Zdroj:	Molecular & Cellular Toxicology. 15:65-73
ISSN:	2092-8467 1738-642X
DOI:	10.1007/s13273-019-0008-x
Popis:	Backgrounds Leucine is involved in various cellular mechanisms, including protein metabolism, insulin signaling, and longevity control. Nevertheless, the contribution of leucine metabolism genes to longevity have not been thoroughly studied.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::b906d0da5af77fd6bdb2802ce9526589 https://doi.org/10.1007/s13273-019-0008-x Zobrazit plný text záznamu Full text from SpringerLink