Correction to: Novel one-pot synthesis of 1-alkyl-2-(aryloxy)methyl-1H-pyrrolo[2,3-b]quinoxalines via copper-free Sonogashira coupling reaction
Autor: | Mahsa Fakharian, Amir Hossein Amin, Mohammad Reza Nabid, Ali Keivanloo |
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Rok vydání: | 2018 |
Předmět: |
chemistry.chemical_classification
010405 organic chemistry One-pot synthesis Sonogashira coupling chemistry.chemical_element General Chemistry 010402 general chemistry 01 natural sciences Copper 0104 chemical sciences chemistry.chemical_compound chemistry Morpholine Polymer chemistry Phenol Propargyl bromide Triethylamine Alkyl |
Zdroj: | Journal of the Iranian Chemical Society. 16:161-162 |
ISSN: | 1735-2428 1735-207X |
DOI: | 10.1007/s13738-018-1507-8 |
Popis: | A novel, simple, and efficient protocol is described for the synthesis of 1-alkyl-2-(aryloxy)methyl-1H-pyrrolo[2,3-b]quinoxalines via the one-pot reaction of phenol or 2-naphthol derivatives, propargyl bromide, and N-alkyl-3-chloroquinoxaline-2-amines in the presence of palladium catalyst. This one-pot reaction is carried out in the absence of any copper salt at room temperature. The reaction product is dependent on the nature of the base used. The use of morpholine, as the base, affords the final cyclized product, and triethylamine only gives the coupling product. |
Databáze: | OpenAIRE |
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