Prostacyclin, Thromboxane A2 Interactions in Haemostasis and Thrombosis

Autor:	S Moncada, J L Amezcua
Rok vydání:	1979
Předmět:	Aspirin biology Chemistry Thromboxane Prostacyclin Hematology Pharmacology medicine.disease Thrombosis Thromboxane A2 chemistry.chemical_compound Physiology (medical) medicine biology.protein Arachidonic acid Thromboxane-A synthase Thrombus medicine.drug
Zdroj:	Pathophysiology of Haemostasis and Thrombosis. 8:252-265
ISSN:	1424-8840 1424-8832
Popis:	Prostacyclin and thromboxane A2 are products of arachidonic acid which play a role in the regulation of haemostatic plug and thrombus formation. Aspirin inhibits the synthesis of both compounds but is more active in blocking TXA2 formation; based on this, aspirin is suggested to have an anti-thrombotic effect. Other possible approaches to the development of anti-thrombotic drugs are discussed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::b8e20e4530982b80c8164cd7c9f0c7bc https://doi.org/10.1159/000214316 Zobrazit plný text záznamu