| Popis: |
Periodontal diseases and disorders of carbohydrate metabolism are comorbid conditions that aggravate each other. There are a number of practical recommendations aimed at preserving the positive results achieved by a dentist as a result of oral sanitation, periodontal and prosthetic treatment. However, they do not fully take into account the features of examination, treatment and rehabilitation of patients suffering from periodontal diseases for a long time, but denying the presence of somatic diseases.The purpose of the study. To evaluate the effectiveness of a complex of post-prosthetic rehabilitation measures using PRP therapy in patients with periodontal diseases and disorders of carbohydrate metabolism.Material and methods. In the period from 2016 to 2021, 441 patients aged 35-55 years who applied to a dental clinic were examined. All patients suffered from chronic generalized periodontitis (CGP), but denied the presence of somatic pathology. As a result of an additional examination in somatic medical organizations (CFOs), 205 patients suffering from CGP were found to have cardiometabolic disorders (impaired glucose tolerance, type 2 diabetes mellitus, arterial hypertension). Prosthetic treatment was performed in 195 patients who were stratified into two groups. Group 1 (120 people) included patients who underwent correction of identified metabolic disorders, group 2 (75 people) – persons who refused further observation by a clinician. By randomization, subgroups were formed in each group: patients of subgroups 1a and 2a received standard post-prosthetic rehabilitation (professional oral hygiene, periodontal treatment), patients of subgroups 1b and 2b additionally underwent local immunocorrection with platelet-enriched autoplasm – PRP (Platelet-rich plasma) therapy. The article presents the results of post-prosthetic rehabilitation of patients with CGP according to clinical (PMA, PI, BOP, OHI-S indices) and immunological (IL-10, IL-8, IL-1ß, TNF-α, sIg A, LDH in oral fluid) indicators obtained after oral sanitation, rehabilitation course, after 3 and 6 months of follow-up.Conclusions. The team approach of dentists and clinicians and the use of periodontal PRP therapy can improve the effectiveness of post-prosthetic rehabilitation measures in periodontal patients with identified comorbid somatic pathology. |
