Interrelationship between depression, anxiety, pain, and treatment adherence in hemophilia: results from a US cross-sectional survey
| Autor: | Michelle Witkop, Angela Lambing, Terry L. Anderson, Cynthia D. Nichols, James Munn, Bartholomew J Tortella |
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| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
endocrine system diseases Cross-sectional study Medicine (miscellaneous) 03 medical and health sciences Social support 0302 clinical medicine Internal medicine 050602 political science & public administration medicine 030212 general & internal medicine Pharmacology Toxicology and Pharmaceutics (miscellaneous) Depression (differential diagnoses) Clotting factor business.industry Health Policy 05 social sciences Chronic pain medicine.disease Comorbidity humanities 0506 political science Patient Health Questionnaire Anxiety medicine.symptom business Social Sciences (miscellaneous) |
| Zdroj: | Patient Preference and Adherence. 13:1577-1587 |
| ISSN: | 1177-889X |
| Popis: | Purpose Depression, anxiety, pain, and treatment adherence have reciprocal effects not characterized extensively in hemophilia. This study explored the relationships between depression, anxiety, chronic pain, and treatment adherence in adults with hemophilia. Patients and methods Adults with self-reported hemophilia A or B completed the cross-sectional IMPACT QoL II survey. Depression (9-item Patient Health Questionnaire [PHQ-9]), anxiety (7-item Generalized Anxiety Disorder scale [GAD-7]), chronic pain (Faces Pain Scale-Revised [FPS-R]), social support (Duke UNC Functional Social Support questionnaire), level of pain control, clotting factor treatment adherence (VERITAS-Pro or -PRN), and previous depression/anxiety were analyzed. Results Among 200 participants (male, 77.3%; female, 22.8%), 54% had PHQ-9 and 52% had GAD-7 scores indicating moderate to severe depression or anxiety without diagnosis of either disorder. Participants with PHQ-9 scores ≥10 (moderate to severe depression) were more likely to have lower treatment adherence than those with PHQ-9 scores |
| Databáze: | OpenAIRE |
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