Toxicological Characteristics Of N-Deacetyllappaconitine Under Chronic Administration In White Rats

Autor: Lola Tishaevna Zakhidova, Tolmas Tolibovich Khamroev, Zafar Isomiddinovich Sanoev, Visola Farmanovna Tukhtasheva, Hilola Akhmedjanovna Rakhmanova, Dilfuza Mir-Takhirovna Saidkhodjaeva
Rok vydání: 2021
Předmět:
Zdroj: The American Journal of Applied Sciences. :34-41
ISSN: 2689-0992
DOI: 10.37547/tajas/volume03issue03-06
Popis: In chronic experiments in laboratory animals, studied toxicological perspective new antiarrhythmic effect of N-deacetyllappaconitine for the treatment of arrhythmic states, an original herbal preparation based on Aconitum leucostonum, Ac.Septentrionale was created. During 2,5 months of intragastric administration in animals exposed to all doses of N-deacetyllappaconitine, no deviations in the parameters of the functioning of the nervous system were found, therefore, this value is the lowest effective (threshold) dose in a chronic experiment.
Databáze: OpenAIRE