| Popis: |
Sample preparation is necessary for the determination of analytes in biological matrices. The presence of endogenous compounds makes biological matrices complex to be analyzed. In recent years, different extraction techniques have been proposed in this area. An innovative approach is solid-phase extraction based on magnetic nanomaterials that can be manipulated using magnetic fields. These materials have been used in extraction fields due to their exclusive features, including extremely large surface area, selective adsorption ability, easy separation only by applying an external magnet, and possibilities for surface modification/functionalization. These materials have been used for the determination of various analytes in biological fluids. In this chapter, various magnetic nanomaterials are classified based on their compositions and the recent applications of these materials in the field of bioanalysis under solid-phase (micro) extraction format are reviewed. Also, the analytical performance of the methods is addressed from a preventative and critical point of view. |
