GENDER-RELATED ALTERATIONS IN FREE FATTY ACIDS AND OXIDATIVE STRESS IN HYPERTENSION CO-MORBIDLY OCCURRING WITH TYPE 2 DIABETES MELLITUS

Autor:	A. J. AKAMO, R. N. UGBAJA, O. ADEMUYIWA, D. I. AKINLOYE, O. T. SOMADE, D. A. OJO, O. A. TALABI, E. A. BALOGUN
Rok vydání:	2019
Předmět:	lipids (amino acids peptides and proteins)
Zdroj:	Journal of Natural Sciences Engineering and Technology. 16:26-38
ISSN:	2315-7461 2277-0593
DOI:	10.51406/jnset.v16i2.1885
Popis:	Increase in plasma free fatty acids (FFAs) concentrations may cause cellular damage via the induction of oxidative stress. The aim of this present study was to investigate FFAs and oxidative stress in hypertension co-morbidly occurring with Type 2 Diabetes Mellitus (T2DM). Age and sex matched control subjects (n=150) and patients (n=470) [hypertensive nondiabetics (HND, n=179), normotensive diabetics (ND, n=132), hypertensive diabetics (HD, n=159)] presenting at the Medical Out-Patient Clinic of the State Hospital, Abeokuta, Nigeria were recruited. Fasting plasma glucose, creatinine, urea, FFAs, thiobarbituric acid reactive substances (TBARS) were determined spectrophotometrically. The presence of either or both diseases resulted in significant increase (p
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::b875feff2fa7168b949ff49e50875e23 https://doi.org/10.51406/jnset.v16i2.1885 Zobrazit plný text záznamu