| Popis: |
Mutational analysis of the cannabinoid receptor will surely contribute to our base of knowledge, building increasingly accurate molecular models of cannabinoid receptors. The ability to tailor future cannabinoid ligands to the receptor will hinge on how well this receptor system is understood. This understanding will potentially yield useful synthetic/modified cannabinergic therapeutic drugs and will very probably serve as future treatment modalities for symptoms of drug withdrawal and addiction. One possibility, on the forefront of pharmacogenomics research, is to create compounds that may activate cannabinoid receptors when there is a loss of endogenous ligand activity or ligand recognition owing to a mutation of those genes encoding the cannabinoid receptors. |
