Scintillating fiber optic dosimeters for breast and prostate brachytherapy
| Autor: | L.M. Moutinho, A. N. Goncalves, H. Freitas, Alcides Pereira, Luis Peralta, S. Pinto, P.J.B.M. Rachinhas, M. J. Costa, I. F. Castro, P. A. O. C. Silva, J.F.C.A. Veloso, J. A. M. Santos, Paulo Simões, J. Melo |
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| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
Dosimeter Materials science business.industry medicine.medical_treatment Brachytherapy medicine.disease 030218 nuclear medicine & medical imaging Radiation therapy 03 medical and health sciences Prostate cancer 0302 clinical medicine Signal-to-noise ratio (imaging) 030220 oncology & carcinogenesis medicine Dosimetry Medical physics business Nuclear medicine Quality assurance Prostate brachytherapy |
| Zdroj: | Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVII. |
| ISSN: | 0277-786X |
| DOI: | 10.1117/12.2254397 |
| Popis: | Brachytherapy is a radiotherapy modality where the radioactive material is placed close to the tumor, being a common treatment for skin, breast, gynecological and prostate cancers. These treatments can be of low-dose-rate, using isotopes with mean energy of 30 keV, or high-dose-rate, using isotopes such as 192Ir with a mean energy of 380 keV. Currently these treatments are performed in most cases without in-vivo dosimetry for quality control and quality assurance. We developed a dosimeter using small diameter probes that can be inserted into the patient's body using standard brachytherapy needles. By performing real-time dosimetry in breast and prostate brachytherapy it will be possible to perform real-time dose correction when deviations from the treatment plan are observed. The dosimeter presented in this work was evaluated in-vitro. The studies consisted in the characterization of the dosimeter with 500 μm diameter sensitive probes (with a BCF-12 scintillating optical fiber) using an inhouse made gelatin breast phantom with a volume of 566 cm3. A breast brachytherapy treatment was simulated considering a tumor volume of 27 cm3 and a prescribed absolute dose of 5 Gy. The dose distribution was determined by the Inverse Planning Simulated Annealing (IPSA) optimization algorithm (ELEKTA). The dwell times estimated from the experimental measurements are in agreement with the prescribed dwell times, with relative error below 3%. The measured signal-to-noise ratio (SNR) including the stem-effect contribution is below 3%. |
| Databáze: | OpenAIRE |
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