Lactic acid bacteria of the Leuconostoc genus with high innate immunity-stimulating activity
| Autor: | Shigeru Abe, Yayoi Nishiyama, Masaki Ishii, Keiko Kataoka, Kazuhisa Sekimizu, Satoshi Nishida |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Colony-forming unit Innate immune system biology food and beverages General Medicine biology.organism_classification Microbiology Lactic acid 03 medical and health sciences chemistry.chemical_compound 030104 developmental biology 0302 clinical medicine chemistry Leuconostoc mesenteroides bacteria Leuconostoc Pharmacology (medical) Leuconostoc carnosum 030212 general & internal medicine General Pharmacology Toxicology and Pharmaceutics Fermentation in food processing Bacteria |
| Zdroj: | Drug Discoveries & Therapeutics. 11:25-29 |
| ISSN: | 1881-784X 1881-7831 |
| DOI: | 10.5582/ddt.2016.01078 |
| Popis: | We screened lactic acid bacteria that exhibited high innate immunity-stimulating activity by monitoring muscle contraction activity in silkworms. Heat-treated fractions of lactic acid bacteria, Leuconostoc carnosum #7-2, Leuconostoc gelidum #4-2, and Leuconostoc mesenteroides 8/11-3, had high (250-460 units/mg) innate immunity-stimulating activity. These lactic acid bacteria proliferated in milk to concentrations of 1 × 106 colony forming unit/mL. The present findings suggest that the silkworm muscle contraction assay is useful for screening lactic acid bacteria with high innate immunity-stimulating activity, and that the assay can be used for the production of fermented foods made from milk. |
| Databáze: | OpenAIRE |
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