Comparison of FK-506 and cyclosporine regimens in pediatric renal transplantation
| Autor: | Velma P. Scantlebury, Ron Shapiro, Laszlo Hopp, Nisan Gilboa, Mark L. Jordan, Nancy Weichler, Richard L. Simmons, Andreas G. Tzakis, Demetrius Ellis |
|---|---|
| Rok vydání: | 1994 |
| Předmět: |
Nephrology
medicine.medical_specialty Chemotherapy business.industry medicine.medical_treatment Immunosuppression medicine.disease Gastroenterology Surgery Discontinuation Transplantation Regimen Prednisone Internal medicine Pediatrics Perinatology and Child Health medicine business hirsutism medicine.drug |
| Zdroj: | Pediatric Nephrology. 8:193-200 |
| ISSN: | 1432-198X 0931-041X |
| DOI: | 10.1007/bf00865477 |
| Popis: | Clinical aspects of FK-506 or cyclosporine immunosuppression regimens were evaluated in 48 consecutive pediatric renal transplant recipients. Tapering and discontinuation of prednisone was employed only in children receiving FK-506 who experienced minor or no rejection episodes during the 1st posttransplant month. At 1 year follow-up, 17 of 22 (77%) of all children with functioning allografts were receiving no prednisone (n=13) or a mean dosage of 0.07 mg/kg per day (n=4). During the 1st month, acute cellular rejection was more common in the FK-506 group (0.58 vs. 0.21 rejections per patient,P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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