pH-MODULATED STEPWISE ELUTION CCC AND ITS APPLICATION TO THE PREPARATIVE SEPARATION OF HYDROXYANTHRAQUINONE COMPOUNDS FROM TRADITIONAL CHINESE MEDICINAL HERBS

Autor:	Tianyou Zhang, F. Edward Chou, Yoichiro Ito, Guoqin Xu, Fuquan Yang
Rok vydání:	2001
Předmět:	Polygonum Chromatography biology Clinical Biochemistry Pharmaceutical Science Hydroxyanthraquinone Pharmacognosy biology.organism_classification Biochemistry Analytical Chemistry chemistry.chemical_compound Countercurrent chromatography chemistry Rheum officinale Polyphenol Phenols Emodin
Zdroj:	Journal of Liquid Chromatography & Related Technologies. 24:1617-1628
ISSN:	1520-572X 1082-6076
DOI:	10.1081/jlc-100104367
Popis:	Analytical and preparative high-speed countercurrent chromatography was successfully used for the separation of hydroxyanthraquinones from traditional Chinese medicine such as Rheum officinale Baill (Dahuang) and Polygonum cuspidatum Sieb. Et Zucc (Huzhang) using pH-modulated stepwise elution. Four major components including chrysophanol, emodin, physcion, and aloe-emodin were isolated each at over 98% purity.
Databáze:	OpenAIRE
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