Cyanofluorination of vinyl ethers enabled by electron donor–acceptor complexes

Autor:	Feng Liu, Ze-Fan Zhu, Jia-Li Liu
Rok vydání:	2019
Předmět:	Single electron chemistry.chemical_compound Chemistry Organic Chemistry Electron donor Selectfluor Acceptor Combinatorial chemistry
Zdroj:	Organic Chemistry Frontiers. 6:241-244
ISSN:	2052-4129
DOI:	10.1039/c8qo01143e
Popis:	An efficient and mild three-component cyanofluorination of vinyl ethers with Selectfluor and TMSCN is described. The reaction protocol is operationally simple, allowing the access to various α-alkoxy-β-fluoronitriles bearing quaternary α-carbons in good to excellent yields. The mechanistic studies indicated that the formation of an electron donor–acceptor (EDA) aggregate and a subsequent single electron transfer (SET) process might be involved in the reaction.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::b7ac31497cccc55440e62dab22b99bcd https://doi.org/10.1039/c8qo01143e Zobrazit plný text záznamu