Association of dietary zinc intake with coronary artery calcium progression: the Multi-Ethnic Study of Atherosclerosis (MESA)
| Autor: | Jingwei Gao, Fei-Fei Huang, Shao-Ling Zhang, Jingfeng Wang, Qing-Yun Hao, Li Yan, Hai-Feng Zhang, Pinming Liu, Zhaoyu Liu |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Ethnic group Medicine (miscellaneous) 030209 endocrinology & metabolism Computed tomography Disease Lower risk Gastroenterology Dietary zinc Mesa 03 medical and health sciences 0302 clinical medicine Internal medicine medicine cardiovascular diseases computer.programming_language Chinese americans 030109 nutrition & dietetics Nutrition and Dietetics medicine.diagnostic_test business.industry nutritional and metabolic diseases Coronary artery calcium business computer |
| Zdroj: | European Journal of Nutrition. 60:2759-2767 |
| ISSN: | 1436-6215 1436-6207 0000-5487 |
| DOI: | 10.1007/s00394-020-02452-5 |
| Popis: | Zinc is considered protective against atherosclerosis; however, the association between dietary zinc intake and cardiovascular disease remains debated. We investigated whether dietary zinc intake was associated with coronary artery calcium (CAC) progression in the Multi-Ethnic Study of Atherosclerosis (MESA). This analysis included 5186 participants aged 61.9 ± 10.2 years (48.8% men; 41.3% white, 25.0% black, 21.6% Hispanic, and 12.1% Chinese American) from the MESA. Dietary zinc intake was assessed by a self-administered, 120-item food frequency questionnaire at baseline (2000–2002). Baseline and follow-up CAC were measured by computed tomography. CAC progression was defined as CAC > 0 at follow-up for participants with CAC = 0 at baseline; and an annualized change of 10 or percent change of ≥ 10% for those with 0 0.05). In this multiethnic population free of clinically apparent cardiovascular disease, higher dietary zinc intake from non-red meat sources was independently associated with a lower risk of CAC progression. The MESA trial was registered at clinicaltrials.gov as NCT00005487. |
| Databáze: | OpenAIRE |
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