Influence ofCordia myxaon chemically induced oxidative stress
| Autor: | M. Afzal, C. Obuekwe, H. Barakat, A.R. Khan |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Nutrition and Dietetics
Antioxidant biology Traditional medicine DPPH medicine.medical_treatment Cordia myxa Aspartate transaminase biology.organism_classification Transaminase chemistry.chemical_compound chemistry Biochemistry medicine Carbon tetrachloride biology.protein Gallic acid Thioacetamide Food Science |
| Zdroj: | Nutrition & Food Science. 39:6-15 |
| ISSN: | 0034-6659 |
| Popis: | Purpose – This paper seeks to investigate Cordia myxa L. (CM) extracts as hepatoprotective agents, through their antioxidant activities.Design/methodology/approach – Oxydative liver damage in rats was induced in Wister rats by two agents: carbon Tetrachloride (CCl4) and thioacetamide (TA). Oxydative damage was evaluated by a measurement of aspartate transaminase (AST), glutamate transaminase (ALT) and Alkaline phosphatase (ALP), in sera of the rats. Several extracts of Cordia myxa were prepared and were fed to experimental animals over a period of two weeks. Liver recovery was assessed by measuring the above hepatic enzymes and their comparison with the control group of animals. Phenolic content of the extracts was measured by Folin‐Ciocalteu reagent and was calculated as gallic acid equivalents. α,α‐diphenyl‐β‐picrylhydrazyl (DPPH) assay was used to measure antiradical activity of the extracts and it was compared with ascorbic acid.Findings – Maximum fruit extract can be obtained by hand‐macerating the p... |
| Databáze: | OpenAIRE |
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