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Introduction: DDB (Dimethyl – 4,4/ – dimethoxy – 5,6,5/,6/ – dimethlene – dioxybi- phenyl – 2,2 – dicarboxylate) is important drug of medicine not expensive since large number of people are using it in virus B and C cases for very large periods extend to many years. The protective of DDB on chemically induced damage was studied in primary cultures of mammals hepatocytes. Results:This work study of cytogenetic and biochemical effect of DDB, in mice using the chromosomes of bone marrow of male and pregnant female shown some changes with liver embryos. Also germ cells of testes given non significant aberration when compared with control. As well as some biochemical parameters in serum and tissues, shown non significant changes in nucleic acid, total protein, total cholesterol, total glucose, total triglycerides and lactate dehydrogenase (LDH). Also, enzyme |
