A novel zinc-binding motif found in two ubiquitous deaminase families

Autor:	Milton H. Saier, Jonathan Reizer, Amos Marc Bairoch, Aiala Reizer, Stewart Buskirk
Rok vydání:	1994
Předmět:	Genetics Saccharomyces cerevisiae Cytidine Cytidine deaminase Biology biology.organism_classification Biochemistry chemistry.chemical_compound chemistry Motif (music) Binding site Aminohydrolase Sequence motif Molecular Biology Peptide sequence
Zdroj:	Protein Science. 3:853-856
ISSN:	0961-8368
DOI:	10.1002/pro.5560030515
Popis:	Two families of deaminases, one specific for cytidine, the other for deoxycytidylate, are shown to possess a novel zinc-binding motif, here designated ZBS. We have (1) identified the protein members of these 2 families, (2) carried out sequence analyses that allow specification of this zinc-binding motif, and (3) determined signature sequences that will allow identification of additional members of these families as their sequences become available.
Databáze:	OpenAIRE
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